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KMID : 0816119990020020240
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Korean Journal of Pediatric Gastroenterolology and Nutrition
1999 Volume.2 No. 2 p.240 ~ p.244
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A Case of Acrodermatitis Enteropathica with Chronic Diarrhea and Disseminated Intravascular Coagulation
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Lee Ji-Eun
Choe Byung-Ho
Hur Jun-Ho
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Abstract
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Acrodermatitis enteropathica, an autosomal recessive disease, usually presents with
severe aural and circumorificial dermatitis, diarrhea, alopecia, intercurrent bacterial
infection during early infancy, and is eventually fatal if left untreated. We report a case
of acrodermatitis enteropathica in a 2-month-old male infant who presented with chronic
diarrhea not responsive to conventional therapy and developed disseminated intravascular
coagulation (DIC). He showed the characteristic eczematoid skin lesions, chronic diarrhea,
failure to thrive, and low serum zinc concenturation. Zn2+was administered
with dramatic improvement of skin lesions, DIC and diarrhea. He rapidly catched up
normal growth and development on continuing zinc supplementation.
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KEYWORD
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Acrodermatitis enteropathica, Zinc, Chronic diarrhea, Disseminated intravascular coagulation,
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